Metabolism of 9, 3"-Diacetylmidecamycin. I. The Metabolic Fate of 9, 3"-Diacetylmidecamycin
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چکیده
منابع مشابه
Radioimmunoassay for metabolites of 9,3"-diacetylmidecamycin, a macrolide antibiotic.
A radioimmunoassay system has been developed for the measurement of two major metabolites of 9,3"-diacetylmidecamycin, Mb-6 and Mb-12. A radioimmunoassay for Mb-6 was performed by using anti-Mb-6 serum and a [125I]tyramined Mb-6 derivative as a radiolabeled antigen. The labeled antigen was prepared by the chloramine T method. The antiserum was obtained from a rabbit immunized with Mb-6 conjugat...
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We have recently shown that interleukin-9 (IL-9) strongly stimulates the proliferation of mouse thymic lymphomas in vitro. Here we report that this factor is also one of the most potent inhibitors of apoptosis induced by dexamethasone (DEX) in such cell lines, even if they do not depend on exogenous factors for growth. For the murine thymic lymphoma BW5147, protection against apoptosis was also...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1982
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.102.8_781